In today’s blog post we will take a look at a package that allows you to keep track of the number of observations that you in- or exclude from your dataset or study population.

In this blog post we are going to fit a stratified Cox regression model by optimising its likelihood function with Optimx::optimx(). Stratified Cox regression models allow one to relax the assumption of proportional hazards over time between different exposure groups.

In this blog post we will optimise a Cox proportional hazard model using a maximum likelihood estimation (MLE) method. For this we are first going to define the likelihood function of our Cox model and its partial first derivatives, sometimes called the score function.

This blog post is a follow up on my previous post on optimising a Weibull regression model using optimx(). This time I’ll try to find a solution for the discrepancy between the confidence interval estimates of the Weibull hazard function estimated with optimx() and flexsurvreg().

In this blog post we will optimise a Weibull regression model by maximising its likelihood function using optimx() from the {optimx} package in R. In my previous blog post I showed how to optimise a Poisson regression model in the same manner.

In this blog post, we will fit a Poisson regression model by maximising its likelihood function using optimx() in R. As an example we will use the lung cancer data set included in the {survival} package.

In my last post I estimated the point estimates for a logistic regression model using optimx() from the optimx package in R. In this post I would like to contine with this model an try to find the standard error (SE) for the derived estimates.

In my last post I used the optim() command to optimise a linear regression model. In this post, I am going to take that approach a little further and optimise a logistic regression model in the same manner.

In this post I would like to show how to manually optimise a linear regression model using the optim() command in R. Usually if you learn how to fit a linear regression model in R, you would learn how to use the lm() command to do this.

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